Genevieve L Taylor, Robert M Joseph, Karl C K Kuban, Laurie M Douglass, Jeff Laux, Bree Andrews, Rebecca C Fry, Wayne A Price, Thomas M O’Shea
Pediatrics. 2021 May;147(5):e2020001040. doi: 10.1542/peds.2020-001040. Epub 2021 Apr 6. PMID: 33824183; PMCID: PMC8086004.
Among children classified as having moderate to severe neurodevelopmental impairment (NDI) at 2 years, 63% had none to mild NDI at 10 years; among children classified as having profound NDI at 2 years, 36% had none to mild NDI at 10 years. We fond minimal to fair agreement between NDI at 2 and 10 years. NDI in infancy, as defined in this study, only weakly predicts NDI in middle childhood. For the parents at risk for delivery of an extremely preterm infant, a hopeful message can be taken from our findings that one-third of surviving children classified as having profound NDI and nearly two-thirds of those classified as having moderate to severe NDI at 2 years had none to mild NDI at 10 years.