Cognitive functioning at age 10 years among children born extremely preterm: A latent profile approach

Timothy Heeren, Robert M Joseph, Elizabeth N Allred, Thomas M O’Shea, Alan Leviton, Karl C K Kuban

Pediatr Res. 2017 Oct;82(4):614-619.

PubMed Link

BACKGROUND:School-age children born EP are more likely than term peers to have multiple neurocognitive limitations.

METHODS: Based on measures of IQ and EF, subgroups of EP children with common neurocognitive function are identified using LPA. Classification of neurocognitive function using IQ and EF is compared to a standard classification based on IQ .

RESULTS / CONCLUSION: LPA identified four neurocognitive profiles in EP children, with 34% of EP children classified normal, 41% low-normal, 17% moderately impaired, and 8% severely impaired. Impaired children exhibited global impairment across cognitive domains, while children in low-normal group tended to have impaired inhibition relative to their reasoning and working memory skills.Both IQ and EF assessments are needed when describing school-age outcome of EP children