Thymus involution and cerebral white matter damage in extremely low gestational age neonates

Joshua David Kuban, Elizabeth N Allred, Alan Leviton

Biol Neonate 2006;90:252-7

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Among newborns who die, those who have cerebral white matter damage are more likely than others to have thymus involution and low thymus weights. We sought to evaluate in a population of preterm newborns who did not die if those who developed a cerebral white matter damage (defined by echolucency) are more likely than others to have thymus involution assessed on chest radiographs. Infants with an EL were more likely to have had early involution than infants without an EL (89% vs. 44%) (p = 0.01).

Video and CD-ROM as a training tool for performing neurologic examinations of 1-year-old children in a multicenter epidemiologic study

Karl C K Kuban, Michael O'Shea, Elizabeth Allred, Alan Leviton, Herbert Gilmore, Adré DuPlessis, Kalpathy Krishnamoorthy, Cecil Hahn, Janet Soul, Sunila E O'Connor, Karen Miller, Paige T Church, Cecilia Keller, Richard Bream, Robin Adair, Alice Miller, Elaine Romano, Haim Bassan, Kathy Kerkering, Steve Engelke, Diane Marshall, Kristy Milowic, Janice Wereszczak, Carol Hubbard, Lisa Washburn, Robert Dillard, Cherrie Heller, Wendy Burdo-Hartman, Lynn Fagerman, Dinah Sutton, Padu Karna, Nick Olomu, Leslie Caldarelli, Melisa Oca, Kim Lohr, Albert Scheiner

J. Child Neurol 2005;20:829-31

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In lieu of traditional training of examiners to identify cerebral palsy on a neurologic examination at age 1 year, we proposed an alternative approach using multimedia training video. Interactive CD-ROM examination training is an efficient and cost-effective means of training both neurologists and non-neurologists to perform structured neurologic examinations in 1-year-old children.