Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in ELGANs

Jonathan L Hecht, Raina N Fichorova, Vanessa F Tang, Elizabeth N Allred, Thomas F McElrath, Alan Leviton, Elgan Study Investigators

Pediatr Res. 2011;69:68-73

PubMed Link

Placental inflammation had (p< 0.01) ↑ blood cytokines (IL-1β, IL-6, and TNF-α), chemokines (IL-8, MIP-1β, RANTES, and I-TAC), adhesion molecules (ICAM-1, ICAM-3, and E-selectin), matrix metalloproteinases (MMP-1 and MMP-9), VEGF and its receptor VEGF-R2, and SAA and CRP in first 3 d.