Antenatal and early postnatal antecedents of parent-reported attention problems at 2 years of age

L Corbin Downey, T Michael O’Shea, Elizabeth N Allred, Karl Kuban, Thomas F McElrath, Diane D Warner, Janice Ware, Jonathan L Hecht, Andrew Onderdonk, Alan Leviton, Extremely Low Gestational Age Newborn (ELGAN) Study

Journal of Pediatrics 2015 166:20-25.

PubMed Link

Antenatal antecedents of attention problems included birth to an unmarried mother, maternal secondhand smoke exposure, severe fetal growth restriction, thrombosis of fetal stem vessels in the chorionic plate, and recovery of an organism from placenta.  All but severe SGA were associated with ADHPDSM, too.  Multiple gestation was associated with a lower risk of ADHPDSM. The only postnatal risk factor for attention problems was recovery of bacteria from a tracheal aspirate. Conclusion: Among ELGANs several potentially modifiable antenatal and perinatal antecedents are associated with increased risk for attention problems and ADHPDSM at 2 years.