Brain damage in preterm newborns and maternal medication:the ELGAN Study

Crystal P Tyler, Nigel Paneth, Elizabeth N Allred, Deborah Hirtz, Karl Kuban, Thomas McElrath, T Michael O’Shea, Cindy Miller, Alan Leviton, ELGAN Study Investigators

Am J Obstet Gynecol. 2012;207:192.e1-9

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After adjustment for potential confounding the risk of QP CP remained elevated among infants of mothers who consumed aspirin ([OR, 3.0; 95 CI, 1.3-6.9) and NSAIDs (OR, 2.4; 95% CI, 1.04-5.8). The risk of DP CP was also associated with NSAID, but only if consumption was not approved by a physician (OR, 3.5; 95% CI 1.1-11.0).