Early blood gas predictors of bronchopulmonary dysplasia in extremely low gestational age newborns

Sudhir Sriram, Joy Condie, Michael D Schreiber, Daniel G Batton, Bhavesh Shah, Carl Bose, Matthew Laughon, Linda J Van Marter, Elizabeth N Allred, Alan Leviton

Int J Pediatr. 2014;2014:210218.

PubMed Link

In models that did not adjust for ventilation, hypoxemia was associated with ↑ risk of severe and very severe BPD; infants with hypercapnea were at increased risk of very severe BPD only. Infants with hypocapnea were at reduced risk of severe BPD. Including ventilation for 14 or more days eliminated associations with hypoxemia and hypercapnea and made the decreased risk of very severe BPD statistically significant.