Early postnatal hypotension and developmental delay at 24 months of age among extremely low gestational age newborns

J Wells Logan, T Michael O’Shea, Elizabeth N Allred, Matthew M Laughon, Carl L Bose, Olaf Dammann, Daniel G Batton, Stephen C Engelke, Alan Leviton, ELGAN Study Investigators

Arch Dis Child Fetal Neonatal Ed. 2011;96:F321-8

PubMed Link

78% of infants in cohort received volume expansion or pressors;. 26% had MDI <70 & 32% had PDI <70. Low MDI & PDI associated with low GA, which in turn, was associated with pressor treatment. After adjusting for potential confounders, none of the indicators of hypotension associated with MDI <70 or PDI <70.