Alan Leviton, Karl C K Kuban, Elizabeth N Allred, Raina N Fichorova, T Michael O’Shea, Nigel Paneth, ELGAN Study Investigators
Early Hum Dev. 2011;87:325-30
↑ SAA on day 1 and ↑of five proteins on day 14, (IL-6, TNF-R2, IL-8, MCP-1, and ICAM-1) increased risk of microcephaly. The ten proteins ↑ on two separate days a week apart predicted microcephaly, but not when elevated on only one day, were CRP, SAA, IL-1β, IL-6, TNF-α, IL-8, MCP-1, ICAM-1, E-SEL, IGFBP-1.