Colonization of second trimester placenta parenchyma

Andrew B Onderdonk, Jonathan L Hecht, Thomas F McElrath, Mary L Delaney, Elizabeth N Allred, Alan Leviton, ELGAN Study Investigators

Am J Obstet Gynecol 2008;199:52.e1-52.e10

PubMed Link

Bx specimens of chorion from 1083 placentas cultured, and placentas examined. Placentas delivered by c/s w/ PET had lowest bacteria (25%). Preterm labor had highest rates, which ↓with ↑GA from 79% at 23 weeks to 43% at 27 wks. Microorgs in placenta associated w/wbc in fetal stem vessels of chorion or in vessels of umb cord.