Early nutrition and weight gain in preterm newborns and the risk of retinopathy of prematurity

Deborah K VanderVeen, Camilia R Martin, Reshma Mehendale, Elizabeth N Allred, Olaf Dammann, Alan Leviton, ELGAN Study Investigators

PLoS One. 2013 May 29;8(5):e64325.

PubMed Link

Greater risk for Type 1 ROP found for infants with lowest ¼ ile receipt of lipids (2.1/1.1, 3.8), total calories (2.2/1.4, 3.6), and carbohydrates (1.7/1.1, 2.9). Zone 1 ROP was associated with lowest quartile lipid or total calorie intake; stage 3 ROP associated with lowest ¼ ile of total calorie. GV in lowest ¼ ile associated with increased risk of ROP, including type 1 ROP. ROP Risk might be reduced by improving nutritional support.