Perinatal systemic inflammatory responses of growth-restricted preterm newborns

T F McElrath, E N Allred, L Van Marter, R N Fichorova, A Leviton, ELGAN Study Investigators

Acta Paediatr. 2013 Oct;102(10):e439-42.

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Severe SGAs (B Wt Z-score <-2) were not at increased risk of systemic inflammation on day 1. On day 14, however, they were more likely to have elevated CRP, IL-1β, IL-6, TNF-α, IL-8, MCP-4, ICAM-1, ICAM-3, E-SEL, MMP-9, VEGF-R2 and/or IGFBP-1, not attributable to delivery indication, bacteremia or ventilation duration.