T Michael O’Shea, Karl C K Kuban, Elizabeth N Allred, Nigel Paneth, Marcello Pagano, Olaf Dammann, Lisa Bostic, Kara Brooklier, Samantha Butler, Donald J Goldstein, Gail Hounshell, Cecelia Keller, Susan McQuiston, Alice Miller, Steve Pasternak, Susan Plesha-Troyke, Joan Price, Elaine Romano, Katherine M Solomon, Amanda Jacobson, Sjirk Westra, Alan Leviton, Extremely Low Gestational Age Newborns Study Investigators
Pediatrics 2008;122:e662-e669
26% of all children had MDI < 70, and 31% had PDI < 70. HUS more associated with low PDI than with low MDI. Children w/o HUS abnormality had lowest probability (23% and 26%) of delayed development. Mod/severe Vmeg associated with 4-fold risk of low PDI and 3-fold risk of low MDI. EL was next best predictor of delay At particularly high risk were infants with bilat cerebellar hemorrhage, Vmeg and bilat/post EL