Positive screening on the Modified-Checklist for Autism in Toddlers (M-CHAT) in Extremely Low Gestational Age Newborns

Karl C K Kuban, T Michael O’Shea, Elizabeth N Allred, Helen Tager-Flusberg, Donald J Goldstein, Alan Leviton

J Pediatr 2009;154:535-540.e1

PubMed Link

Odds for screening + on M-CHAT ↑ 23-fold for those unable to sit or stand and 7-fold if unable to walk. Children with QP were 13 X more likely to screen +, and those with HP 4 X more likely to screen +. Children with major vision or hearing impairments were 8 X more likely to screen +. Odds for screening + were increased 13-fold with MDI <55 and > than 4-fold for MDI 55-69. Even after motor, cognitive, visual, & hearing impairments eliminated, 10% screened +: double expected rate.